Hiroaki Ikesue

Distinct effects of nonselective Rho-kinase inhibitor fasudil and selective Rho-kinase 2 inhibitor KD025 on serotonin and dopamine release in the nucleus accumbens of mice

This study compares the effects of fasudil and KD025 on serotonin and dopamine release in the nucleus accumbens of mice, finding distinct roles for Rho-kinase 1 and 2 in neurotransmitter regulation.

Cortical excitatory and inhibitory neuron deficits may underlie the cognitive and social impairments in a mouse model of schizophrenia with exonic Reln deletion

This paper investigates the role of Reelin in schizophrenia by analyzing a mouse model with exonic Reln deletion, finding deficits in excitatory and inhibitory neurons and suggesting therapeutic potential for Reelin replacement.

Twinfilin-1 phosphorylation in reelin signaling regulates actin dynamics and spine development

This study identifies Twinfilin-1 phosphorylation as a key component of reelin signaling that regulates actin dynamics and spine development in neurons.