Author

Kara M. Foshay

University of Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Bohou WuiD· 2 shared Bruce T. LahniD· 2 shared Croydon J. Fernandes· 2 shared Guoping FaniD· 2 shared Jae Hyun Lee· 2 shared Li ZhangiD· 2 shared Andy Peng XiangiD· 1 shared Becky X. Xiao· 1 shared

Activity by Year

2021-2024 · peak 1/yr

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10 top collaborators · 42 mutual co-author links

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2 shared papersDevelopmental Biology

Bohou WuORCID

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2 papers

Recent·Most cited

Mechanistic basis of lineage restriction

Bohou Wu, Jae Hyun Lee, Kara M. Foshay, Li Zhang, Croydon J. Fernandes, Boyang Gao, Xiaoyang Dou, Chris Z. Zhang, Guoping Fan, Becky X. Xiao, Bruce T. Lahn

The paper links cellular developmental potency to genomic transcriptional potency, showing that gene occlusion via chromatinization restricts lineage potential.

bioRxiv · Aug 7, 2024 · PreprintDevelopmental Biology

Capacity to erase gene occlusion is a defining feature distinguishing naive from primed pluripotency

Kara M. Foshay, Jae Hyun Lee, Li Zhang, Croydon J. Fernandes, Bohou Wu, Jedidiah Gaetz, Samuel W. Baker, Timothy J. Looney, Andy Peng Xiang, Guoping Fan, Bruce T. Lahn

The paper identifies gene occlusion erasure as a defining difference between naive and primed pluripotency states, showing Esrrb-dependent deocclusion sustains naive pluripotency.

bioRxiv · May 4, 2021 · PreprintMolecular Biology