Heteroplasmic Mitochondrial Genetic Variation in the Human Heart
Liying Xue, Xianbang Sun, Jesse D. Moreira, Yi Li, Karan K. Smith, Robert F. Padera, Marc E. Lenburg, Daniel A Levy, Emelia J. Benjamin, Deepa Mangalat Gopal, Chunyu Liu, Jessica L. Fetterman
The paper examines heteroplasmic mitochondrial genetic variants in human cardiac tissues and finds they differ from those in blood and skeletal muscle, with higher variant counts in cardiac tissue linked to age.
bioRxiv · Jul 13, 2022 · PreprintGenetics