Author

Jessica L. Fetterman

Boston UniversityORCID 0000-0002-9286-7538Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Developmental Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:differential expression· 3 Organism:human· 3 Assay:whole-genome sequencing· 3 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Chunyu LiuiD· 3 shared Daniel A LevyiD· 2 shared Xianbang Sun· 2 shared Achilleas PitsillidesiD· 1 shared Adam C. GoweriD· 1 shared Adolfo CorreaiD· 1 shared Amanda PinheiroiD· 1 shared Brian E. CadeiD· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersGenetics

Chunyu LiuORCID

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Author profile →

4 papers

Recent·Most cited

The Dlk1-Dio3 noncoding RNA cluster coordinately regulates mitochondrial respiration and chromatin structure to establish proper cell state for muscle differentiation

Amanda Pinheiro, Christopher A. Petty, Kevin Cabrera, Eric Palanques Tost, Adam C. Gower, Madison Marano, Ethan M. Leviss, Matthew J. Boberg, Jawahar Mahendran, Payton Bock, Chelsea E. Stephens, Jessica L. Fetterman, Francisco J. Naya

Development · Nov 29, 2024Peer-reviewedDevelopmental Biology

Heteroplasmic Mitochondrial Genetic Variation in the Human Heart

Liying Xue, Xianbang Sun, Jesse D. Moreira, Yi Li, Karan K. Smith, Robert F. Padera, Marc E. Lenburg, Daniel A Levy, Emelia J. Benjamin, Deepa Mangalat Gopal, Chunyu Liu, Jessica L. Fetterman

The paper examines heteroplasmic mitochondrial genetic variants in human cardiac tissues and finds they differ from those in blood and skeletal muscle, with higher variant counts in cardiac tissue linked to age.

bioRxiv · Jul 13, 2022 · PreprintGenetics

A Bioinformatics Pipeline for Estimating Mitochondria DNA Copy Number and Heteroplasmy Levels from Whole Genome Sequencing Data

Stephanie L. Battle, Daniela Puiu, TOPMed mtDNA Working Group, Joost Verlouw, Linda Broer, Eric Boerwinkle, Kent D. Taylor, Jerome I. Rotter, S.S Rich, Megan L. Grove, Nathan Pankratz, Jessica L. Fetterman, Chunyu Liu, Dan E. Arking

This paper presents a bioinformatics pipeline to estimate mitochondrial DNA copy number and heteroplasmy levels from whole genome sequencing data, showing improved accuracy in capturing mitochondrial genetic features.

NAR Genomics and Bioinformatics · Mar 31, 2022Peer-reviewedGenetic & Genomic Medicine

Presence and Transmission of Mitochondrial Heteroplasmic Mutations in Human Populations of European and African Ancestry

Chunyu Liu, Jessica L. Fetterman, Yong Qian, Xianbang Sun, Kaiyu Yan, Thomas Blackwell, Achilleas Pitsillides, Brian E. Cade, Heming Wang, Laura M. Raffield, Leslie A. Lange, Pramod Anugu, Gonçalo Abecasis, L. Adrienne Cupples, Susan S Redline, , Daniel A Levy

The paper examines the concordance and characteristics of mitochondrial heteroplasmic mutations in maternal pairs of European and African ancestry, finding higher concordance in close relatives and associations with age and nuclear genome regions.

Mitochondrion · Jul 21, 2021Peer-reviewedGenetics