Intestinal challenges shape the polarisation of protective dural memory CD4 T cells
Aaron Fleming, Rafael Di Marco Barros, David A Posner, Colin Y.C. Lee, Andrew P. Stewart, Zewen Kelvin Tuong, Karen Neish, Ana Peñalver, Mia Cabantous, Nathan Richoz, Anaïs Portet, Katherine Harcourt, Eleanor Gillman, David Ruano‐Gallego, Gad M. Frankel, , Menna Ruth Clatworthy
This study shows that intestinal immunological challenges shape the polarization of dural CD4 T cells, which provide protective memory against pathogens.
bioRxiv · Sep 9, 2025 · PreprintImmunology