Author

Karin Hayashi

Kyoto University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Hirohide SaitoiD· 2 shared Belinda Kaswandy· 1 shared Hirohisa Ohno· 1 shared Hiroki OnoiD· 1 shared Itsuki Abe· 1 shared Mai UedaiD· 1 shared Maya Lopez· 1 shared Megumi Mochizuki· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersDevelopmental Biology

Hirohide SaitoORCID

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2 papers

Recent·Most cited

Transient let-7/miR-98 reprograms primed pluripotency to induce naivehuman PSCs

Yoshihiko Fujita, Moe Hirosawa, Karin Hayashi, Hiroki Ono, Belinda Kaswandy, Mai Ueda, Maya Lopez, Takuya Yamamoto, Yasuhiro Takashima, Hirohide Saito

This paper identifies miR-98-5p as a let-7 family microRNA that enhances naive human PSC induction by repressing NR6A1 and activating BMP2/4 signaling, improving resetting efficiency to ~80%.

bioRxiv · Oct 14, 2025 · PreprintDevelopmental Biology

Split RNA switch: Programmable and precise control of gene expression by ensemble of pre- and post-translational regulation

Itsuki Abe, Hirohisa Ohno, Megumi Mochizuki, Karin Hayashi, Hirohide Saito

The paper introduces split RNA switches that enhance gene regulation specificity by integrating multiple RNA switches through protein splicing, improving ON/OFF ratios and enabling multi-input synthetic circuits.

bioRxiv · Sep 25, 2024 · PreprintSynthetic Biology