Cheating the cheater: Suppressing false positive enrichment during biosensor-guided biocatalyst engineering
Vikas D. Trivedi, Karishma Mohan, Todd C. Chappell, Zachary J. S. Mays, Nikhil U. Nair
The paper addresses false positive enrichment in biosensor-guided biocatalyst engineering by desensitizing biosensors and using orthogonal pre-screens to reduce cheater cells during FACS.
ACS Synthetic Biology · Dec 16, 2021Peer-reviewedSynthetic Biology