Author

Zachary J. S. Mays

Tufts University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:non-human primate· 1

Frequent Co-Authors

Nikhil U. NairiD· 2 shared Debika ChoudhuryiD· 1 shared Karishma Mohan· 1 shared Todd C. Chappell· 1 shared Vikas D. TrivediiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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2 shared papersSynthetic Biology

Nikhil U. NairORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintMar 20, 2026

Substrate transport limits phenylalanine ammonia-lyase activity in engineered Lacticaseibacillus rhamnosus GG

Debika Choudhury, Zachary J. S. Mays, Nikhil U. Nair

This study evaluates different lactic acid bacteria as hosts for expressing phenylalanine ammonia-lyase (PAL) and identifies strategies to enhance enzymatic activity in whole-cell biocatalysts.

DOI 10.64898/2026.03.19.713057

non-human primateexperimental assay

𝕏 PostBluesky

Synthetic BiologyACS Synthetic BiologyPeer-reviewedDec 16, 2021

Cheating the cheater: Suppressing false positive enrichment during biosensor-guided biocatalyst engineering

Vikas D. Trivedi, Karishma Mohan, Todd C. Chappell…·Nikhil U. Nair

The paper addresses false positive enrichment in biosensor-guided biocatalyst engineering by desensitizing biosensors and using orthogonal pre-screens to reduce cheater cells during FACS.

22 citations

experimental assaydrug response / drug discovery

𝕏 PostBluesky