Vikas D. Trivedi

This paper develops molecular probes to manipulate specific subpopulations in microbial communities using bacteriocins and validates them in synthetic populations.

This paper describes a method to discover protein-small molecule hybrids using pharmacophore-driven antibody discovery on yeast, showing that screening outcomes are pharmacophore-dependent.

This paper introduces a metabolic coordinator, Gal3pMC, that enables efficient activation of the GAL regulon across diverse substrates, improving growth rates and substrate utilization in yeast.

The paper evaluates yeast-bacterial cell-cell interactions using flow cytometry and FACS to characterize nanobody-antigen binding.

This study shows that yeast can adapt rapidly to non-native substrates with minimal metabolic engineering by integrating non-native genes with a native regulon system.

The paper addresses false positive enrichment in biosensor-guided biocatalyst engineering by desensitizing biosensors and using orthogonal pre-screens to reduce cheater cells during FACS.

This study quantifies how cell surface charge and environmental factors affect the binding of pediocin PA-1 to microbial species, showing that charged non-target species reduce its potency in mixed communities.