The human papillomavirus L2 protein in the capsid is an ensemble of related structures poised to exit the virus particle
Changin Oh, Huaxin Yu, Patrick M Buckley, Frank Horrigan, Kashif Mehmood, Jeongjoon Choi, Jun Liu, Daniel DiMaio
This study uses cryo-EM and computational methods to model the structure of HPV16 L2 protein within the capsid, revealing its conformational flexibility and positioning for virus entry.
bioRxiv · Aug 21, 2026 · PreprintMicrobiology