Changin Oh

This study uses cryo-EM and computational methods to model the structure of HPV16 L2 protein within the capsid, revealing its conformational flexibility and positioning for virus entry.

The paper identifies SNX12 as a retromer adaptor critical for HPV16 infection and shows how cargo-adaptor interactions specify retromer coat architecture through structural and functional analyses.

This paper introduces the Toroidal Search Algorithm (TSA), a metaheuristic optimization method that outperforms existing techniques in high-dimensional and bounded search spaces, with applications in mathematical oncology parameter estimation.