Author

Kassandra R. Bruner

University of Arizona

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Jennifer H. SterniD· 2 shared Susma Ghimire· 2 shared Thea Fletcher· 2 shared Tyler J. Marx· 2 shared Anastasiia VasilevaiD· 1 shared Daniel J. DruckeriD· 1 shared David G. BesselseniD· 1 shared Frank Anthony DucaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPhysiology

Jennifer H. SternORCID

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2 papers

Recent·Most cited

Glucagon receptor signaling is indispensable for the healthspan effects of caloric restriction in aging male mice

Kassandra R. Bruner, Isabella R. Byington, Tyler J. Marx, Anastasiia Vasileva, Thea Fletcher, Susma Ghimire, India J. Zappia, Yashika Shaju, Janan Zeng, Hallie R. Wachsmuth, Thadeus W. Carlyon, David G. Besselsen, Daniel J. Drucker, Frank Anthony Duca, Jennifer H. Stern

This study shows that glucagon receptor signaling is essential for the healthspan benefits of caloric restriction in aging male mice, as its absence reduces lifespan and impairs metabolic improvements.

GeroScience · Sep 25, 2025Peer-reviewedPhysiology

12 weeks of voluntary wheel running restores glucagon sensitivity in middle-aged mice

Tyler J. Marx, Kassandra R. Bruner, Susma Ghimire, Thea Fletcher, Jennifer H. Stern

This study shows that 12 weeks of voluntary wheel running restores glucagon sensitivity in middle-aged mice without affecting glucose homeostasis.

bioRxiv · May 23, 2025 · PreprintPhysiology