Author

David G. Besselsen

University of ArizonaORCID 0000-0001-5890-0501Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Anastasiia VasilevaiD· 1 shared April M WagneriD· 1 shared Chiu-Hsieh HsuiD· 1 shared Christian BimeiD· 1 shared Daniel J. DruckeriD· 1 shared Eugene W. GerneriD· 1 shared Frank Anthony DucaiD· 1 shared Hallie R. Wachsmuth· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPhysiology

Anastasiia VasilevaORCID

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2 papers

Recent·Most cited

Cell BiologyVirusesPeer-reviewedSep 26, 2025

Preclinical evaluation of the efficacy of α-Difluoromethylornithine and Sulindac against SARS-CoV-2 infection

Natalia A. Ignatenko, Hien T. Trinh, April M Wagner…·David G. Besselsen

This study evaluates DFMO and Sulindac's antiviral efficacy against SARS-CoV-2 in cell lines and mice, showing age- and sex-dependent protective effects.

DOI 10.3390/v17101306

mouseexperimental assay

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PhysiologyGeroSciencePeer-reviewedSep 25, 2025

Glucagon receptor signaling is indispensable for the healthspan effects of caloric restriction in aging male mice

Kassandra R. Bruner, Isabella R. Byington, Tyler J. Marx…·Jennifer H. Stern

This study shows that glucagon receptor signaling is essential for the healthspan benefits of caloric restriction in aging male mice, as its absence reduces lifespan and impairs metabolic improvements.

4 citations

mouseexperimental assay

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