Daniel J. Drucker

This paper shows that D-allulose-induced GLP-1 enhances insulin action via left-sided vagal afferents, improving glucose tolerance more effectively than GLP-1 receptor agonists in mice.

The paper shows that combining GLP-1R agonists with ectopic hepatic GLP-1R expression enhances weight loss in mice by increasing energy expenditure and reducing food intake.

The paper shows that telocytes relay signals from enteroendocrine cells to ILC2s, amplifying the tuft cell circuit in response to feeding.

This study shows that glucagon receptor signaling is essential for the healthspan benefits of caloric restriction in aging male mice, as its absence reduces lifespan and impairs metabolic improvements.