Author

Kate D Crawford

Gladstone Institutes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Organism:yeast· 2 Organism:bacteria (other)· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

Santiago C. LopeziD· 2 shared Seth L. ShipmaniD· 2 shared Asim G KhaniD· 1 shared Hani GoodarziiD· 1 shared Santi Bhattarai-KlineiD· 1 shared Sierra K. LeariD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersBioengineering

Santiago C. LopezORCID

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Author profile →

2 papers

Recent·Most cited

High Throughput Variant Libraries and Machine Learning Yield Design Rules for Retron Gene Editors

Kate D Crawford, Asim G Khan, Santiago C. Lopez, Hani Goodarzi, Seth L. Shipman

The paper uses high-throughput variant libraries and machine learning to identify design rules for improving retron gene editors in both yeast and human genome editing.

Nucleic Acids Research · Nov 19, 2024Peer-reviewedBioengineering

Improved architectures for flexible DNA production using retrons across kingdoms of life

Santiago C. Lopez, Kate D Crawford, Sierra K. Lear, Santi Bhattarai-Kline, Seth L. Shipman

The paper improves retron architectures to enhance DNA production across different organisms, leading to more efficient genome editing.

Nature Chemical Biology · Dec 23, 2021Peer-reviewedSynthetic Biology