Disease progression Mendelian randomization of risk factors for kidney function decline in chronic kidney disease and the general population
Aristomo Andries, Venexia M. Walker, Artemis A. Briasouli, Maria K Sobczyk, Jie Zheng, Mathias Gorski, Iris M. Heid, Stein Ivar Hallan, Kate Tilling, Humaira Rasheed, Bjørn Olav Åsvold, Ben Michael Brumpton, Tom R. Gaunt
This study uses Mendelian randomization to identify risk factors for kidney function decline in CKD and the general population, finding causal effects of type-2 diabetes and high TSH.
medRxiv · Sep 8, 2026 · PreprintGenetic & Genomic Medicine