Lucy Riglin

Longitudinally stable, brain-based predictive models mediate the relationships between childhood cognition and socio-demographic, psychological and genetic factors

The paper develops brain-based predictive models for childhood cognition using multimodal MRI data from the ABCD study, showing stability over time and partial mediation of socio-demographic, psychological, and genetic factors.

Is genetic liability to ADHD and ASD causally linked to educational attainment?

This paper uses Mendelian randomization to investigate causal links between genetic liability to ADHD/ASD and educational attainment, finding distinct causal effects for ADHD and ASD.

Using genetics to examine a general liability to childhood psychopathology

The paper examines whether genetic liability to schizophrenia and ADHD contributes to shared risks across childhood psychiatric diagnoses through a general psychopathology factor.

Identifying novel subtypes of irritability using a developmental genetic approach

This paper identifies five irritability trajectory classes in a longitudinal cohort, linking early-onset patterns to ADHD and late-onset patterns to depression, suggesting distinct developmental origins.

The role of rare copy number variants in depression

The paper investigates the role of rare copy number variants (CNVs) in depression, finding that neurodevelopmental CNVs are associated with increased depression risk.