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Kathryn M. Denecke

University of Washington

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Developmental Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

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Hao Yuan KuehiD· 1 shared Lihua CheniD· 1 shared Nicholas A. PeaseiD· 1 shared Peter Habib Gerges· 1 shared

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Developmental BiologyDevelopmentPeer-reviewedDec 1, 2024

A timed epigenetic switch balances T and ILC lineage proportions in the thymus

Nicholas A. Pease, Kathryn M. Denecke, Lihua Chen…·Hao Yuan Kueh

The paper shows that delaying Bcl11b activation via an epigenetic switch increases ILC generation and reduces T cell output in the thymus by redirecting progenitors at the T/ILC branchpoint.

3 citations

mousebulk RNA-seq

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