NeuroscienceFrontiers in Synaptic NeurosciencePeer-reviewed
Alpha1-Adrenergic Receptor Mediated Long-Term Depression at CA3-CA1 Synapses Can be Induced via Accumulation of Endogenous Norepinephrine and is Preserved Following Noradrenergic Denervation
Katie Dyer-Reaves, Anthoni M. Goodman, Amy R. Nelson, Lori L. McMahon
The paper shows that 1AR-mediated LTD at CA3-CA1 synapses can be induced by endogenous NE accumulation and remains functional even after significant NA innervation loss.
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