Lori L. McMahon

The paper shows forskolin reverses O-GlcNAcylation-induced decrease in GABAAR current amplitude by unmasking neurosteroid site accessibility on GABAARs.

This study examines how sex and time-of-day affect hippocampal neurophysiology and spatial memory, finding sex-specific differences in memory performance and synaptic activity across circadian cycles.

This study identifies hyperexcitability in dentate granule cells of TgF344-AD rats, characterized by altered passive and active membrane properties contributing to increased excitability and reduced high-frequency firing.

This study investigates fear extinction memory and basolateral amygdala (BLA) synaptic dysfunction in TgF344-AD rats, finding distinct impairments in AD compared to non-pathological aging.

The study finds heightened β-adrenergic receptor function in the TgF344-AD rat model enhances synaptic plasticity and preserves learning and memory in early AD.

This paper shows that X-ray activation of cerium-doped LSO particles can increase synaptic activity via Channelrhodopsin-2 in hippocampal neurons.

This study shows that AD mouse models have impaired clock gene expression and disrupted diurnal regulation of hippocampal inhibitory transmission and spatial memory.

This study shows that neonatal hyperoxia exposure in mice leads to heightened CA3-CA1 synaptic function in early adulthood, potentially contributing to hippocampal shrinkage and cognitive deficits.

This study shows that increased BIN1 expression in neurons leads to hyperexcitability, which is modulated by Tau, suggesting a role for BIN1 in Alzheimer's disease pathogenesis.

This study shows that increased O-GlcNAcylation reduces GABAergic currents and neuronal output in hippocampus by affecting synaptic and intrinsic excitability.

The paper shows that 1AR-mediated LTD at CA3-CA1 synapses can be induced by endogenous NE accumulation and remains functional even after significant NA innervation loss.

This study shows that neonatal hyperoxia impairs hippocampal mitochondrial function in young adult mice, potentially contributing to cognitive deficits.

This paper demonstrates that LSO:Ce inorganic scintillators can activate ChR2 and modify synaptic function without harming neurons, suggesting their potential as a non-invasive light delivery system for optogenetics.