Cancer BiologybioRxivPreprint
KRas, in addition to Tp53 is a driver for early carcinogenesis and a molecular target in a mouse model of invasive gastro-esophageal adenocarcinoma
Akanksha Anand, Linus R. Schömig, Sebastian Lange…·Michael Quante
This study identifies KRAS mutation as a driver of invasive gastro-esophageal adenocarcinoma in a mouse model, showing its synergistic role with Tp53 or Rb1 loss and potential as a therapeutic target.
DOI 10.1101/2024.05.07.592904