Molecular BiologybioRxivPreprint
Targeted knockdown of the PAF49 component of the PAF53/PAF49 heterodimer causes the degradation of PAF53.
Rachel McNamar, Katrina N. Rothblum, Lawrence Ian Rothblum
The paper shows that knocking down PAF49 in mammalian cells leads to the degradation of PAF53, while core RNA polymerase I subunits remain stable.
DOI 10.1101/2021.01.27.428437