Author

Rachel McNamar

University of OklahomaORCID 0000-0001-5422-5617Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1 Organism:yeast· 1

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Katrina N. Rothblum· 2 shared Lawrence Ian RothblumiD· 2 shared Bruce A. KnutsoniD· 1 shared Zakaria Abu-Adas· 1 shared

Activity by Year

2019-2021 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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2 shared papersMolecular Biology

Katrina N. Rothblum

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJan 27, 2021

Targeted knockdown of the PAF49 component of the PAF53/PAF49 heterodimer causes the degradation of PAF53.

Rachel McNamar, Katrina N. Rothblum, Lawrence Ian Rothblum

The paper shows that knocking down PAF49 in mammalian cells leads to the degradation of PAF53, while core RNA polymerase I subunits remain stable.

DOI 10.1101/2021.01.27.428437

mouseexperimental assay

𝕏 PostBluesky

Molecular BiologyJournal of Biological ChemistryPeer-reviewedNov 14, 2019

Inducible degron-dependent depletion of the RNA polymerase I associated factor PAF53 demonstrates it is essential for cell growth and allows for the analysis of functional domains

Rachel McNamar, Zakaria Abu-Adas, Katrina N. Rothblum…·Lawrence Ian Rothblum

The paper demonstrates that PAF53 is essential for mammalian rDNA transcription and mitotic growth, and identifies functional domains within the protein.

15 citations

𝕏 PostBluesky