Author

Kazuki Imadegawa

Waseda University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Akihiko TakashimaiD· 1 shared Hikaru Kurahashi· 1 shared Kotaro Kawasaki· 1 shared Mizuho Oishi· 1 shared Shiho Aoki· 1 shared Toru AsahiiD· 1 shared Wataru OnoderaiD· 1 shared Yoshiyuki SoedaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Akihiko TakashimaORCID

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1 paper

Recent·Most cited

E3 ligase Praja1 mediates ubiquitination and degradation of microtubule-associated protein Tau

Shiho Aoki, Wataru Onodera, Akihiko Takashima, Kotaro Kawasaki, Kazuki Imadegawa, Hikaru Kurahashi, Mizuho Oishi, Toru Asahi, Yoshiyuki Soeda

This study identifies Praja1 as an E3 ligase that ubiquitinates and degrades Tau, a key protein in tauopathies, and shows evolutionary conservation of this interaction.

FEBS Journal · Nov 3, 2025Peer-reviewedBiochemistry