Author

Yoshiyuki Soeda

Gakushuin UniversityORCID 0000-0001-9657-4102Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1 Approach:optimal transport· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. HattoriiD· 1 shared Akihiko TakashimaiD· 1 shared Akihiko TakashimaiD· 1 shared Boxiao Zhao· 1 shared Gen MatsumotoiD· 1 shared Hideaki� YoshimuraiD· 1 shared Hikaru Kurahashi· 1 shared Hiroko BannaiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. HattoriORCID

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2 papers

Recent·Most cited

E3 ligase Praja1 mediates ubiquitination and degradation of microtubule-associated protein Tau

Shiho Aoki, Wataru Onodera, Akihiko Takashima, Kotaro Kawasaki, Kazuki Imadegawa, Hikaru Kurahashi, Mizuho Oishi, Toru Asahi, Yoshiyuki Soeda

This study identifies Praja1 as an E3 ligase that ubiquitinates and degrades Tau, a key protein in tauopathies, and shows evolutionary conservation of this interaction.

FEBS Journal · Nov 3, 2025Peer-reviewedBiochemistry

Inducing aggresome and stable tau aggregation in Neuro2a cells with an optogenetic tool.

Shigeo Sakuragi, Tomoya Uchida, Naoki Kato, Boxiao Zhao, Toshiki Takahashi, A. Hattori, Yoshihiro Sakata, Yoshiyuki Soeda, Akihiko Takashima, Hideaki� Yoshimura, Gen Matsumoto, Hiroko Bannai

This paper introduces OptoTau, an optogenetic tool that induces different tau aggregation forms in Neuro2a cells based on blue light exposure patterns.

Biophysics and Physicobiology · Jan 1, 2024Peer-reviewedBiophysics