Escape from Cell Uptake: Drug-Free Cancer Therapeutics Regulated Hydrophobicity and Negative Charge
Kazuki Moroishi, Masahiko Nakamoto, Satoshi Fujita…·Michiya Matsusaki
This study investigates how varying grafting degrees of PVA-U affect its cytotoxicity in response to tumor microenvironment stimuli, showing that PVA-U15 exhibits the highest selectivity due to its aggregation and cell membrane adsorption properties.