Author

Masahiko Nakamoto

The University of OsakaORCID 0000-0003-4570-5429Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Michiya MatsusakiiD· 2 shared Kazuki Moroishi· 1 shared Kazunori KadotaiD· 1 shared Marie KawaharaiD· 1 shared Rentaro SakamotoiD· 1 shared Ryohei KatayamaiD· 1 shared Satoshi Fujita· 1 shared Tatsuya FukutaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

Michiya MatsusakiORCID

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2 papers

Recent·Most cited

BiochemistryMaterials Today BioPeer-reviewedDec 30, 2025

Escape from Cell Uptake: Drug-Free Cancer Therapeutics Regulated Hydrophobicity and Negative Charge

Kazuki Moroishi, Masahiko Nakamoto, Satoshi Fujita…·Michiya Matsusaki

This study investigates how varying grafting degrees of PVA-U affect its cytotoxicity in response to tumor microenvironment stimuli, showing that PVA-U15 exhibits the highest selectivity due to its aggregation and cell membrane adsorption properties.

1 citation

experimental assay

𝕏 PostBluesky

BiochemistryACS Applied Materials & InterfacesPeer-reviewedOct 21, 2025

Emergence of a Cell-Guided Multivalent Ligand of Enzymes on Cancer Cells Triggered by Click Reaction between Hetero Nano-Assemblies

Rentaro Sakamoto, Yuki Koba, Masahiko Nakamoto…·Michiya Matsusaki

This study develops a system where a click reaction between hetero-nano-assemblies triggers the emergence of multivalent ligands that selectively inhibit cancer cells overexpressing CAIX under hypoxia.

2 citations

experimental assaydrug response / drug discovery

𝕏 PostBluesky