Non-canonical Sodium Channel Isoforms Underlie Chamber Specific Cardiac Excitability
Colin J. Clark, Christian Anderson, Alex Dou, Jason M. Dierdorff, Jason D. Galpin, Lionel Gissot, Samantha L. Thompson, Hannah Choi, Jin‐Young Yoon, Daniel T. Infield, Jared M. McLendon, Peter Bronk, Keane Leeds, Ryan L. Boudreau, Bum‐Rak Choi, , Christopher A. Ahern
This study identifies chamber-specific contributions of non-NaV1.5 sodium channel isoforms to cardiac excitability using a chemical-genetic mouse model and electrophysiological recordings.
bioRxiv · Aug 27, 2025 · PreprintPhysiology