Author
University of IowaORCID 0000-0003-1923-5312Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Cecilia M. Borghese, Netrang G Desai, Pranavi Garlapati…·Marcel P Goldschen-Ohm
The paper identifies a conserved atomic interaction in inhibitory neurotransmitter receptors that stabilizes channel gating and explains disease-linked mutations.
Yichen Liu, Jason D. Galpin, Christopher A. Ahern, Francisco Bezanilla
The paper investigates the molecular mechanism of fast sodium channel inactivation using fluorescence spectroscopy and electrophysiology, proposing an alternative 'lock and key' model.
Colin J. Clark, Christian Anderson, Alex Dou…·Christopher A. Ahern
This study identifies chamber-specific contributions of non-NaV1.5 sodium channel isoforms to cardiac excitability using a chemical-genetic mouse model and electrophysiological recordings.
Cecilia M. Borghese, Jason D. Galpin, Samuel Eriksson Lidbrink…·Marcel P Goldschen-Ohm
The paper identifies a single main-chain hydrogen bond in the β2 subunit M2-M3 linker that inhibits GABAA receptor pore opening and is required to keep the unliganded channel closed.