Actl7b-deficiency leads to mislocalization of LC8 type dynein light chains and disruption of murine spermatogenesis
Gina Esther Merges, Lena Arévalo, Andjela Kovacevic, Keerthika Lohanadan, Dirk G. de Rooij, Carla Simon, Melanie Jokwitz, Walter Witke, Hubert Schorle
This study shows that Actl7b deficiency in mice causes spermatogenic arrest and cytoskeletal defects in spermatids due to mislocalization of LC8 dynein light chains.
Development · Oct 6, 2023Peer-reviewedDevelopmental Biology