Macrophage-derived reactive oxygen species promote Salmonella aggresome formation contributing to bacterial antibiotic persistence
Xiao Chen, Kefan Fang, Бо Ли, Yingxing Li, Yuehua Ke, Weixin Ke, Tian Tian, Yifan Zhao, Linqi Wang, Jing Geng, Mark C. Leake, Fan Bai
This study shows that macrophage-derived ROS induce Salmonella aggresome formation, leading to antibiotic persistence through dormancy and resuscitation capability.
iMeta · Jun 22, 2025Peer-reviewedBiophysics