Fan Bai

This study shows glioblastoma hijacks astrocyte ribosomes via tunneling nanotubes, reprograms the tumor translatome to promote malignancy, and identifies INTS12 as a therapeutic target.

The paper shows that aggresomes in E. coli store mRNA under stress, aiding rapid recovery by protecting mRNA from degradation and facilitating translation reactivation.

This study shows that macrophage-derived ROS induce Salmonella aggresome formation, leading to antibiotic persistence through dormancy and resuscitation capability.

The paper identifies Th2-like malignant cells in CTCL supported by a B cell-rich microenvironment through single-cell and spatial transcriptomics analysis.

The paper maps somatic mutations and clonal expansions in normal human tissues across nine organs, revealing organ-specific patterns of mutation accumulation and clonal evolution.

This study uses single-cell RNA sequencing to analyze immune responses in COVID-19 patients, identifying key immune cell changes and molecular pathways linked to disease severity.

The paper uses whole-genome sequencing to predict cell-of-origin for primary liver cancers, finding heterogeneity in origin predictions across cancer types.

This study compares the effects of different surface attachment methods on Escherichia coli physiology in vivo, finding no significant differences in growth rate, size, or intracellular pH.