Myosin forces elicit an F-actin structural landscape that mediates mechanosensitive protein recognition
Ayala G. Carl, Matthew J. Reynolds, Xiaoyu Sun, Pinar S. Gurel, Donovan Y.Z. Phua, Keith Hamilton, Lin Mei, John W. Watters, Yasuharu Takagi, Alex J. Noble, James R. Sellers, Gregory M. Alushin
The paper shows myosin forces alter F-actin structure, creating a landscape that -catenin recognizes, revealing a mechanism for mechanosensitive signaling.
Nature · Apr 22, 2026Peer-reviewedBiophysics