Gregory M. Alushin

This study uses cryo-EM to visualize E. coli RNAP collisions with roadblocks and other RNAPs, revealing structural changes and mechanisms of collision resolution.

The paper shows myosin forces alter F-actin structure, creating a landscape that -catenin recognizes, revealing a mechanism for mechanosensitive signaling.

This study uses cryo-EM and myosin motors to show that wild-type α-actinin-4 forms two binding states with F-actin, while the K255E variant only forms strong bonds, revealing a force-induced transition mechanism for catch bonding.

This study shows afadin and vinculin enhance cadherin-catenin complex binding to F-actin, stabilizing it through cooperative interactions and promoting filament curvature.

This study reveals how zyxin assemblies coordinate actin nucleation and crosslinking to repair stress fibers in response to mechanical forces.

This study investigates how fascin's structural plasticity enables flexible actin bundle formation through cryo-EM, tomography, and modeling.