Author

John W. Watters

Rockefeller UniversityORCID 0000-0001-5786-8861Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Assay:cryo-EM· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:E. coli· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Shixin LiuiD· 3 shared Gregory M. AlushiniD· 2 shared Alex J. NobleiD· 1 shared Andreas U. Müller· 1 shared Ayala G. Carl· 1 shared Bryce J. Katch· 1 shared Dan ZhangiD· 1 shared Donovan Y.Z. PhuaiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiophysics

Shixin LiuORCID

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Author profile →

4 papers

Recent·Most cited

BiophysicsbioRxivPreprintApr 29, 2026

Structural principles of transcriptional collisions

John W. Watters, Andreas U. Müller, Xiangwu Ju…·Shixin Liu

This study uses cryo-EM to visualize E. coli RNAP collisions with roadblocks and other RNAPs, revealing structural changes and mechanisms of collision resolution.

1 citation

E. colicryo-EM

𝕏 PostBluesky

BiophysicsNaturePeer-reviewedApr 22, 2026

Myosin forces elicit an F-actin structural landscape that mediates mechanosensitive protein recognition

Ayala G. Carl, Matthew J. Reynolds, Xiaoyu Sun…·Gregory M. Alushin

The paper shows myosin forces alter F-actin structure, creating a landscape that -catenin recognizes, revealing a mechanism for mechanosensitive signaling.

11 citationstop 4%

cryo-EMmicroscopy & imaging analysis

𝕏 PostBluesky

BiophysicsCellPeer-reviewedJan 28, 2026

A non-catalytic role for RFC in PCNA-mediated processive DNA synthesis

Gabriella N. L. Chua, Emily C. Beckwitt, Victoria Miller-Browne…·Shixin Liu

This study reveals a non-catalytic role for RFC in stabilizing PCNA-Polδ interactions during DNA synthesis, essential for processive replication.

3 citationstop 4%

experimental assaychromatin & epigenetic regulation

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Molecular BiologyNature Structural & Molecular BiologyPeer-reviewedNov 27, 2025

Kinetic control of mammalian transcription elongation

Yukun Wang, Xizi Chen, Maximilian Kümmecke…·Shixin Liu

This study develops a single-molecule platform to analyze mammalian transcription elongation dynamics and identifies kinetic regulation by elongation factors.

6 citations

experimental assay

𝕏 PostBluesky