Author

Kelly Blease

Elements Biosciences (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Organism:human· 1 Research Focus:imputation· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Junhua ZhaoiD· 2 shared Semyon KruglyakiD· 2 shared Adam Fries· 1 shared Adeline Mah· 1 shared Adriana Roginski Guetter· 1 shared Andrew Altomare· 1 shared Andrew D. Price· 1 shared Andrew M. BoddickeriD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Junhua ZhaoORCID

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2 papers

Recent·Most cited

Low-pass sequencing plus imputation using avidity sequencing displays comparable imputation accuracy to sequencing by synthesis while reducing duplicates

Jeremiah H. Li, Karrah Findley, Joseph K. Pickrell, Kelly Blease, Junhua Zhao, Semyon Kruglyak

This study compares imputation accuracy between avidity sequencing and sequencing by synthesis, finding comparable performance with lower duplication rates in avidity sequencing.

G3 Genes Genomes Genetics · Dec 1, 2023Peer-reviewedGenomics

Sequencing by avidity enables high accuracy with low reagent consumption

Sinan Arslan, Francisco J. Garcia, Minghao Guo, Matthew William Kellinger, Semyon Kruglyak, Jake A. LeVieux, Adeline Mah, Haosen Wang, Junhua Zhao, Chunhong Zhou, Andrew Altomare, John Bailey, Matthew B. Byrne, Chiting Chang, Steve X. Chen, , Jordan M. Neysmith

This paper introduces avidity sequencing, a new chemistry that improves sequencing accuracy and reduces reagent use, enabling applications like single-cell RNA-seq and whole-genome sequencing.

Nature Biotechnology · May 25, 2023Peer-reviewedGenomics