Spatiotemporal Control of Genetic and Epigenetic Editing through Covalent Tethering of CRISPR Nanoparticles to Zwitterionic Microgels
Joshua P. Graham, Erika E. Wheeler, Kent J. Leach, Tomas Gonzalez‐Fernandez
This paper introduces a method to covalently tether CRISPR nanoparticles to microgels for sustained and localized gene editing in human cells.
bioRxiv · Sep 22, 2026 · PreprintBioengineering