Author

Kentaro Ohkuni

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:yeast· 3 Approach:experimental assay· 2 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Munira A. BasraiiD· 3 shared Michael CostanzoiD· 2 shared Wei-Chun Au· 2 shared Charles Boone· 1 shared Charles M. BooneiD· 1 shared Daniel R. ZenkluseniD· 1 shared Emma M Hicks· 1 shared Evelyn Suva· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersGenetics

Munira A. BasraiORCID

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3 papers

Recent·Most cited

Yra2 regulates proteolysis of Cse4 to prevent its mislocalization to non-centromeric regions for chromosomal stability in budding yeast

Prashant K Mishra, Kentaro Ohkuni, Pascal Raymond, Emma M Hicks, Michael Costanzo, Charles M. Boone, Daniel R. Zenklusen, Munira A. Basrai

This paper identifies Yra2's role in ubiquitin-mediated proteolysis of Cse4 to prevent its mislocalization and maintain chromosomal stability in budding yeast.

Genetics · Oct 29, 2026Peer-reviewedGenetics

Reduced Gene Dosage of Histone H4 Prevents CENP-A Mislocalization in Saccharomyces cerevisiae

Jessica R. Eisenstatt, Kentaro Ohkuni, Wei-Chun Au, Olivia Preston, Evelyn Suva, Michael Costanzo, Charles Boone, Munira A. Basrai

This study identifies genes that contribute to mislocalization of overexpressed Cse4 and shows reduced H4 dosage facilitates Cse4 sumoylation and mislocalization, leading to synthetic dosage lethality.

bioRxiv · May 29, 2020 · PreprintGenetics

N-terminal sumoylation of centromeric histone H3 variant Cse4 regulates its proteolysis to prevent mislocalization to non-centromeric chromatin

Kentaro Ohkuni, Reuben Levy-Myers, Jack Warren, Wei-Chun Au, Yoshimitsu Takahashi, Richard E. Baker, Munira A. Basrai

This study identifies K65 as a SUMO site on Cse4 and shows that sumoylation regulates its ubiquitin-mediated proteolysis to prevent mislocalization and maintain genome stability.

G3 Genes Genomes Genetics · Feb 8, 2018Peer-reviewedMolecular Biology