Genome-wide CRISPR screens in T helper cells reveal pervasive cross-talk between activation and differentiation
Johan Henriksson, Xi Chen, Tomás Gomes, Ubaid Ullah, Kerstin B Meyer, Ricardo Miragaia, Graham Duddy, Jhuma Pramanik, Kosuke Yusa, Riitta Lahesmaa, Sarah A Teichmann
The paper uses CRISPR screens in T helper cells to identify genes involved in Th2 differentiation and activation, revealing cross-talk between these processes.
bioRxiv · Dec 28, 2017 · PreprintImmunology