Riitta Lahesmaa

This study shows that disrupting the CIP2A gene reduces T cell-driven inflammation in experimental autoimmune encephalomyelitis.

This study shows Satb1 interacts with cohesin and CTCF to regulate chromatin organization and gene expression during T cell development.

The paper evaluates the type 1 error rate in bisulfite sequencing analysis of umbilical cord blood samples and finds that permutation-based significance analysis reduces it, with minimal differential methylation associated with clinical variables except sex.

The paper characterizes the CIP2A interactome in Th17 cells using affinity-purification mass spectrometry and validates key interactions, revealing associations with RNA processing and other cellular processes.

LonGP is a Gaussian process regression model for longitudinal studies that handles time-varying covariates and non-linear effects, showing performance on simulated and real -omics data.

The paper uses CRISPR screens in T helper cells to identify genes involved in Th2 differentiation and activation, revealing cross-talk between these processes.