Author

Xi Chen

Southern University of Science and TechnologyORCID 0000-0003-4251-7035Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xi Chen13 papers · AstraZeneca (United States)

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

Jhuma PramanikiD· 3 shared Bidesh MahataiD· 2 shared Angela Riedel· 1 shared Aws Al-DekaiD· 1 shared Christopher J. Ward· 1 shared Clara Veiga-VillauriziD· 1 shared Gozde Kar· 1 shared Graham Duddy· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersImmunology

Jhuma PramanikORCID

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3 papers

Recent·Most cited

ImmunologyCell ReportsPeer-reviewedMay 1, 2026

Glucocorticoid receptor and RUNX transcription factors cooperatively drive CD8 T cell dysfunction in human cancer

Christopher J. Ward, Soura Chakraborty, Sanu Korumadathil Shaji…·Bidesh Mahata

This study identifies GR-RUNX cooperation in driving CD8 T cell dysfunction in human cancer through transcriptional and chromatin analyses.

6 citationstop 1%

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Cancer BiologybioRxivPreprintNov 9, 2018

Single-cell RNA sequencing reveals a dynamic stromal niche within the evolving tumour microenvironment

Sarah Davidson, Mirjana Efremova, Angela Riedel…·Sarah A. Teichmann

This study uses single-cell RNA sequencing to analyze stromal cell changes in murine melanoma, identifying distinct CAF populations and their roles in immune suppression across tumor development.

DOI 10.1101/467225

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ImmunologybioRxivPreprintDec 28, 2017

Genome-wide CRISPR screens in T helper cells reveal pervasive cross-talk between activation and differentiation

Johan Henriksson, Xi Chen, Tomás Gomes…·Sarah A Teichmann

The paper uses CRISPR screens in T helper cells to identify genes involved in Th2 differentiation and activation, revealing cross-talk between these processes.

DOI 10.1101/196022

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