Author

Kevin Brueck

Boston University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Archana JayaramaniD· 1 shared Christoph ReinhardtiD· 1 shared Hulbert YangiD· 1 shared Lucien P. GaroiD· 1 shared Marcel StrueveiD· 1 shared Markus BosmanniD· 1 shared Matthew M. HelmkampiD· 1 shared Sarah WalachowskiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Archana JayaramanORCID

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1 paper

Recent·Most cited

Proton-Activated Chloride Channel 1 (PACC1) is essential for innate host defense against bacterial sepsis

Lucien P. Garo, Kevin Brueck, Sarah Walachowski, Archana Jayaraman, Marcel Strueve, Shuang Xu, Hulbert Yang, Matthew M. Helmkamp, Seung Hoan Choi, Christoph Reinhardt, Markus Bosmann

This study identifies PACC1 as essential for phagolysosomal acidification and host defense against bacterial sepsis, showing impaired bacterial clearance and increased inflammation in PACC1-deficient mice.

Proceedings of the National Academy of Sciences · Apr 6, 2026Peer-reviewedImmunology