Author

Matthew M. Helmkamp

Boston UniversityORCID 0009-0005-7657-3301Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Archana JayaramaniD· 1 shared Christoph ReinhardtiD· 1 shared Hulbert YangiD· 1 shared Kevin Brueck· 1 shared Lucien P. GaroiD· 1 shared Marcel StrueveiD· 1 shared Markus BosmanniD· 1 shared Sarah WalachowskiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Archana JayaramanORCID

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1 paper

Recent·Most cited

ImmunologyProceedings of the National Academy of SciencesPeer-reviewedApr 6, 2026

Proton-Activated Chloride Channel 1 (PACC1) is essential for innate host defense against bacterial sepsis

Lucien P. Garo, Kevin Brueck, Sarah Walachowski…·Markus Bosmann

This study identifies PACC1 as essential for phagolysosomal acidification and host defense against bacterial sepsis, showing impaired bacterial clearance and increased inflammation in PACC1-deficient mice.

1 citation

mousehuman

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