Christoph Reinhardt

This study identifies PACC1 as essential for phagolysosomal acidification and host defense against bacterial sepsis, showing impaired bacterial clearance and increased inflammation in PACC1-deficient mice.

This study identifies a novel CD36-TSP-1 signaling pathway that modulates platelet-RBC interaction, promoting thrombus formation and contributing to abdominal aortic aneurysm pathology.

This study shows that aging microbiota impairs Treg cell function through TNF signaling, leading to inflammation and immune aging.