Markus Bosmann

This study identifies Oncostatin M (OSM) as a critical regulator of pulmonary host responses during influenza and bacterial pneumonia, revealing non-canonical signaling pathways.

This study identifies PACC1 as essential for phagolysosomal acidification and host defense against bacterial sepsis, showing impaired bacterial clearance and increased inflammation in PACC1-deficient mice.

This study identifies the Kyn-AHR-TF axis as a prothrombotic pathway in SARS-CoV-2 infection, showing increased kynurenine and AHR activation in mice and humans.

This study uses human stem cell-derived alveolar type 2 cells to model SARS-CoV-2 infection, revealing rapid inflammatory responses and drug efficacy against the virus.