Discovery and Characterization of a Pan-betacoronavirus S2-binding antibody
Nicole V. Johnson, Steven C. Wall, Kevin J. Kramer, Clinton Holt, Sivakumar Periasamy, Simone I. Richardson, Nelia P. Manamela, Naveenchandra Suryadevara, Emanuele Andreano, Ida Paciello, Giulio Pierleoni, Giulia Piccini, Ying Huang, Pan Ge, James D. Allen, , Ivelin S. Georgiev
The paper identifies a pan-betacoronavirus antibody that binds the S2 subunit of spike proteins and induces Fc-dependent antiviral responses, offering insights into non-neutralizing antibody protection.
Structure · Sep 25, 2024Peer-reviewedMolecular Biology