Author

Alexander A. Bukreyev

The University of Texas Medical Branch at GalvestonORCID 0000-0002-0342-4824Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adolfo García‐SastreiD· 1 shared Alexandria A. Abu-Shmais· 1 shared Anastasija ČupićiD· 1 shared Andrea R. ShiakolasiD· 1 shared Barton F. HaynesiD· 1 shared Beatriz M. A. FontouraiD· 1 shared Chengjin YeiD· 1 shared Clinton HoltiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Adolfo García‐SastreORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Mutations in SARS-CoV-2 Nsp1 are critical determinants of viral pathogenicity in mice

Nathaniel D. Jackson, Fuchun Zhou, Anastasija Čupić, Tolga Çağatay, Haiping Hao, Vinay Shivanna, Ruby A. Escobedo, Kevin Chiem, Chengjin Ye, Lisa Miorin, Beatriz M. A. Fontoura, Adolfo García‐Sastre, Alexander A. Bukreyev, Luis Martínez‐Sobrido

This study identifies critical residues in SARS-CoV-2 Nsp1 that determine viral pathogenicity in mice by reducing replication and immune response severity.

bioRxiv · Aug 19, 2026 · PreprintMicrobiology

Discovery and Characterization of a Pan-betacoronavirus S2-binding antibody

Nicole V. Johnson, Steven C. Wall, Kevin J. Kramer, Clinton Holt, Sivakumar Periasamy, Simone I. Richardson, Nelia P. Manamela, Naveenchandra Suryadevara, Emanuele Andreano, Ida Paciello, Giulio Pierleoni, Giulia Piccini, Ying Huang, Pan Ge, James D. Allen, , Ivelin S. Georgiev

The paper identifies a pan-betacoronavirus antibody that binds the S2 subunit of spike proteins and induces Fc-dependent antiviral responses, offering insights into non-neutralizing antibody protection.

Structure · Sep 25, 2024Peer-reviewedMolecular Biology