Author

James D. Allen

Cleveland ClinicORCID 0000-0002-3798-706XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Ted M. RossiD· 3 shared Giuseppe Andrea SauttoiD· 2 shared Ivelin S. GeorgieviD· 2 shared Matthew H. ThomasiD· 2 shared Alexander A. BukreyeviD· 1 shared Alexandria A. Abu-Shmais· 1 shared Amanda LynchiD· 1 shared Andrea R. ShiakolasiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

Ted M. RossORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Computationally Optimized H1 and H3 Hemagglutinin Messenger RNA Vaccines Confer Broad Protective Immunity Against Modern Influenza Viruses

James D. Allen, Jessica M. Medina, Camila Carla da Silva Caetano, Matthew H. Thomas, Amanda Lynch, Ted M. Ross

This study develops COBRA HA mRNA vaccines that induce broad immunity against diverse influenza strains in mice.

bioRxiv · Sep 10, 2026 · PreprintImmunology

Design and characterization of broadly protective influenza A(H3N2) vaccine candidates using protein language models

Victoria Howard, James D. Allen, Matthew H. Thomas, Giuseppe Andrea Sautto, Ted M. Ross, Ivelin S. Georgiev

This study designs influenza A(H3N2) vaccine candidates using protein language models and machine learning, showing two candidates provide broad protection against current and drifted strains in mice.

bioRxiv · Aug 31, 2026 · PreprintImmunology

Discovery and Characterization of a Pan-betacoronavirus S2-binding antibody

Nicole V. Johnson, Steven C. Wall, Kevin J. Kramer, Clinton Holt, Sivakumar Periasamy, Simone I. Richardson, Nelia P. Manamela, Naveenchandra Suryadevara, Emanuele Andreano, Ida Paciello, Giulio Pierleoni, Giulia Piccini, Ying Huang, Pan Ge, James D. Allen, , Ivelin S. Georgiev

The paper identifies a pan-betacoronavirus antibody that binds the S2 subunit of spike proteins and induces Fc-dependent antiviral responses, offering insights into non-neutralizing antibody protection.

Structure · Sep 25, 2024Peer-reviewedMolecular Biology