Detailed in vivo characterization of the players and impact of individual loop extrusion trajectories
Ruiqi Han, Yike Huang, Michelle Robers, Mikhail D. Magnitov, Iwan Vaandrager, Amin Allahyar, Marjon J.A.M. Verstegen, Kexin Zhang, Elzo de Wit, Wouter L. de Laat, Peter H.L. Krijger
This study uses TACL to analyze individual cohesin loop extrusion trajectories in vivo, revealing new roles for cohesin subunits and their interactions with CTCF and chromatin structure.
bioRxiv · Jan 4, 2023 · PreprintGenomics