Author

Ruiqi Han

University Medical Center UtrechtORCID 0000-0001-7212-0747Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:spatial domain detection· 2 Assay:DNA methylation· 1 Assay:Hi-C· 1

Frequent Co-Authors

Marjon J.A.M. Verstegen· 2 shared Peter H.L. KrijgeriD· 2 shared Wouter L. de LaatiD· 2 shared Amin AllahyariD· 1 shared Anna-Karina FelderiD· 1 shared Christian Valdes‐QuezadaiD· 1 shared Elzo de WitiD· 1 shared Iwan Vaandrager· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenomics

Marjon J.A.M. Verstegen

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintJan 4, 2023

Detailed in vivo characterization of the players and impact of individual loop extrusion trajectories

Ruiqi Han, Yike Huang, Michelle Robers…·Peter H.L. Krijger

This study uses TACL to analyze individual cohesin loop extrusion trajectories in vivo, revealing new roles for cohesin subunits and their interactions with CTCF and chromatin structure.

6 citations

humanChIP-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintOct 5, 2021

Building regulatory landscapes: enhancer recruits cohesin to create contact domains, engage CTCF sites and activate distant genes

Niels J. Rinzema, Konstantinos Sofiadis, Sjoerd J. D. Tjalsma…·Wouter L. de Laat

This study shows enhancers recruit cohesin to form chromatin domains, engage CTCF sites, and activate distant genes, with transcription factors and mediator required for all distances but cohesin specifically for long-range activation.

8 citations

ChIP-seqDNA methylation

𝕏 PostBluesky